Public Research

The science behind the botanicals.

A curated library of peer-reviewed, PubMed-indexed studies on ginseng and canine wellness. We share this so pet parents and veterinarians can read the evidence directly — and form their own view.

9Peer-reviewed studies

2007–26Two decades of evidence

PubMedIndependently indexed

Section 14 studies

Key research

Peer-reviewed studies that frame how ginseng and related botanicals may support cognition, vitality and quality of life in dogs.

Senior dogs, cognition and quality of life01

Panax Ginseng in combination with brewers' yeast (Gerivet) as a stimulant for geriatric dogs: a controlled, randomized, blinded study

J Vet Pharmacol Ther2007

In a randomised, blinded trial, owners of geriatric dogs given Panax ginseng with brewers' yeast reported significant improvements in alertness, playfulness and overall wellbeing over 8 weeks, with no adverse effects on blood or urine. The study highlights the potential of ginseng to support quality of life in older dogs.

PubMed · PMID 17610402Read

Black ginseng, anti-inflammatory effects in dogs02

Serum metabolic profiling reveals potential anti-inflammatory effects of the intake of black ginseng extracts in beagle dogs

Molecules2020

Beagles fed black ginseng extract for 8 weeks showed serum metabolite changes consistent with anti-inflammatory processes, with glycine and β-alanine identified as candidate biomarkers — the first study to suggest an anti-inflammatory effect of black ginseng in dogs.

PubMed · PMID 32824755Read

Black ginseng, energy and immune metabolism in dogs03

Metabolic changes in serum metabolome of beagle dogs fed black ginseng

Metabolites2021

Using NMR-based metabolomics, researchers tracked changes in beagle serum after 8 weeks of black ginseng, finding metabolite shifts consistent with enhanced energy metabolism and immune function — and demonstrating how metabolomics can be applied to pet wellness.

PubMed · PMID 33352805Read

2024 review of ginseng use in dogs and cats04

Herbal paw-sibilities: potential use and challenges of Astragalus membranaceus and Panax species (ginseng) in diets intended for cats and dogs

Anim Front2024

A 2024 review examining the potential use and challenges of ginseng (and astragalus) in dog and cat diets, outlining bioactive compounds, processing methods and the evidence base for functional botanicals in companion-animal nutrition.

PubMed · PMID 38910952Read

Section 23 studies

Relevant, but more specific

Targeted studies that explore particular mechanisms and outcomes in dogs.

Korean red ginseng and body composition05

Anti-obesity effects of Korean red ginseng extract in healthy beagles

Acta Biochim Pol2019

Healthy beagles fed a Korean red ginseng diet for 8 weeks showed significant decreases in body weight, body condition score and leptin, with CT confirming reduced body fat — and no adverse blood changes, suggesting a potential role in healthy weight management.

PubMed · PMID 31269358Read

Ginseng polysaccharides and canine intestinal inflammation06

Ginseng polysaccharides ameliorate DSS-induced inflammatory bowel disease by regulating gut microbiota in dogs

Front Vet Sci2026

In dogs with induced inflammatory bowel disease, ginseng polysaccharides eased clinical symptoms, reduced C-reactive protein and restored gut microbiota balance — supporting their potential as a natural candidate for canine IBD.

PubMed · PMID 41585527Read

Ginseng and canine immune cells07

Ginseng total saponin enhances the phagocytic capacity of canine peripheral blood phagocytes

Vet Immunol Immunopathol2008

An in vitro study found ginseng total saponin enhanced the phagocytic (clean-up) capacity of canine white blood cells, mediated by TNF-α released from immune cells — pointing to an immune-supporting effect in dogs.

PubMed · PMID 18457364Read

Section 32 studies

Useful mainly as supporting evidence

Studies that add context on absorption, formulation and specific applications.

American ginseng absorption in dogs08

A systematic study of the dissolution and relative bioavailability of four ginsenosides from Panax quinquefolius L. in beagle dogs

J Ethnopharmacol2016

A pharmacokinetic study in beagles compared three formulations of American ginseng, finding that ultrafine granular powder delivered the highest absorption and fastest dissolution of key ginsenosides — useful context for formulation and bioavailability.

PubMed · PMID 26976765Read

Male dog reproductive study09

Effects of different processed forms of Panax ginseng on sperm motility and biochemical parameters in dogs

J Anim Sci Technol2025

A crossover study in beagles compared white, red and black ginseng over 60 days; black ginseng significantly improved sperm motility and velocity versus the other forms, with no adverse biochemical effects and no change in testosterone.

PubMed · PMID 40519621Read

These studies are shared for educational purposes only. They are not a substitute for veterinary advice, and Pet Longevity Co. does not make disease-treatment claims. Pet-specific efficacy statements are published only once validated through veterinary, scientific and regulatory review. For any health concern, please consult your veterinarian.